Unnatural α-amino ethyl esters from diethyl malonate or ethyl β-bromo-α-hydroxyiminocarboxylate

• Eloi P. Coutant,
• Vincent Hervin,
• Glwadys Gagnot,
• Candice Ford,
• Racha Baatallah and
• Yves L. Janin

Beilstein J. Org. Chem. 2018, 14, 2853–2860, doi:10.3762/bjoc.14.264

• -bromo-α-hydroxyiminocarboxylate and various alkylfuranes. Keywords: α-amino ester; α-hydroxyimino ester; [2 + 4] cycloadditions; [2 + 3] cycloadditions; Knoevenagel; nitrosoacrylate; Suzuki–Miyaura; Introduction Our current work on the chemistry of imidazo[1,2-a]pyrazin-3(7H)-one luciferins [1] has